Amoxicillin is a semi-synthetic broad-spectrum penicillin, which interferes with the synthesis of bacterial cell walls by binding to bacterial penicillin-binding proteins to exert a bactericidal effect. Its role is characterized by a broad spectrum, not resistant to penicillinase. Amoxicillin is effective against Streptococcus pneumoniae, hemolytic Streptococcus, non-penicillinase-producing Staphylococcus, Enterococcus faecalis and other aerobic Gram-positive cocci, Escherichia coli, Proteus mirabilis, Salmonella, and influenza Haemophilus, Neisseria gonorrhoeae and other aerobic Gram-negative bacteria that do not produce β-lactamase strains, and Helicobacter pylori have good antibacterial activity. Amoxicillin capsules are suitable for infections caused by sensitive bacteria that do not produce β-lactamase, including upper respiratory tract infections, such as otitis media, sinusitis, pharyngitis, tonsillitis, etc.; genitourinary tract infections; skin and soft tissue infections; lower respiratory tract infections , such as acute bronchitis, pneumonia, etc.; acute simple gonorrhea can also be used to treat typhoid fever, typhoid carriers and leptospirosis.
Amoxicillin can also be combined with clarithromycin and lansoprazole to eradicate gastroduodenal Helicobacter pylori and reduce the recurrence rate of peptic ulcer. However, it should be noted that patients with infectious mononucleosis are prone to rashes when using this product, so it should be avoided. Since a small amount of amoxicillin can be secreted in breast milk, it may cause allergies to the baby after taking it by the nursing mother, so the pros and cons should be weighed when using it for breastfeeding women. This product can pass through the placenta, and pregnant women should weigh the pros and cons when using it. When infants, children, and the elderly use it, they should read the instructions carefully and take the medicine according to the doctor’s advice. Patients with severe renal impairment need to adjust the dosage according to the endogenous creatinine clearance rate, please read the instructions carefully and take the medicine according to the doctor’s advice. Patients must be asked about their drug allergy history in detail before taking the medicine, and a penicillin skin test should be done. In case of anaphylactic shock, rescue should be performed on the spot, and treatment measures such as keeping the airway unobstructed, oxygen inhalation, and application of epinephrine and glucocorticoids should be taken. Patients allergic to penicillin and positive penicillin skin test are contraindicated.
Post time: Dec-30-2022