Drug knowledge popularization:Efficacy and function of Ivermectin


Ivermectin is an avermectin antiparasitic drug, belonging to a semi-synthetic broad-spectrum antiparasitic drug. It is effective for most (but not all) nematodes of various life cycles, and for microfilaria of onchocerciae, but not for adults; It is also effective for roundworm only in the intestine.

This product has a selective inhibitory effect, which can increase the permeability of cell membrane to chloride ions, cause hyperpolarization of nerve cells or muscle cells, and paralyze or kill parasites. Ivermectin can not penetrate human blood brain barrier.


Main treatment

Ivermectin can be used to treat onchocerciasis, roundworm disease, hookworm, roundworm, whipworm, pinworm infection

Applicable symptoms

Ivermectin can alleviate the infection symptoms caused by such parasites as Trichinella spiralis, hookworm, roundworm, whipworm and pinworm, such as skin damage, lymph node disease and eye damage.


The combination of ivermectin and warfarin, an anticoagulant, may lead to an increase in the international standardized ratio (INR), and should be vigilant in the use of drugs.

If you are taking other drugs, please consult your doctor before taking medicine, and tell your doctor how many diseases you have been diagnosed and the treatment plan you are receiving.


Ivermectin should be used according to the prescribed dose. Excessive use may cause ataxia, slow breathing, tremor, eyelid droop, decreased activity, vomiting and dilated pupils.

In case of overdose, emesis and gastric lavage should be carried out as soon as possible. If necessary, cathartic drugs and other conventional antitoxic treatment can be given again.

In case of accidental poisoning, supportive therapy (including supplement of body fluid and electrolyte, oxygen or mechanical ventilation) can be carried out as needed. In case of clinically obvious hypotension, vasopressor should be given.


Post time: Mar-10-2023