Umthombo: 39 Health Network
Ingcebiso engundoqo: xa i-cephalosporin antibiotics kunye nezinye iziyobisi ze-hypoglycemic zidibana notywala, zingakhokelela kwi-"disulfiram efana" yokusabela kwetyhefu.Izinga lokuxilongwa ngokungalunganga kolu hlobo lwempendulo yetyhefu liphezulu ukuya kuma-75%, kwaye abo banzulu banokufa.Ugqirha ukhumbuza ukuba akufuneki usele utywala kwiiveki ezimbini emva kokuthatha amayeza okubulala iintsholongwane, kwaye ungachukumisi ukutya okunxilisayo kunye neziyobisi ezifana namanzi eHuoxiang Zhengqi kunye netshokolethi yeJiuxin.
Kwabakho umkhuhlane nengqele ekhaya kangangeentsuku eziliqela.Emva konyango, malunga nama-35 abantu abazithembayo basela kunye;Emva kokutya iziyobisi ze-hypoglycemic, sela iwayini encinci ukukhulula iminqweno ... Oku akuqhelekanga kumadoda amaninzi.Noko ke, iingcali zalumkisa nxamnye nokuthotywa “kwiwayini encinane” emva kokugula.
Kule nyanga iphelileyo, amadoda amaninzi e-Guangzhou aneempawu zokusela ezinjengokubetha kwentliziyo, ukuxinana kwesifuba, ukubila, isiyezi, intlungu yesisu kunye nokugabha kwitafile yewayini.Nangona kunjalo, xa besiya esibhedlele, bafumanisa ukuba babengenabo utywala, izifo zentliziyo kunye ne-cerebrovascular nezinye iingxaki.Kwavela ukuba ngaphambi kokuba baye isidlo sakusihlwa, bathathe i-antibiotics kunye neziyobisi ze-hypoglycemic.
Oogqirha babonisa ukuba emva kokuthatha i-cephalosporin antibiotics, i-imidazole derivatives, i-sulfonylureas kunye ne-biguanides, xa sele ibonakaliswe etywaleni, iya kukhokelela kule "disulfiram efana ne-reaction" eye ingahoywa ixesha elide ekusebenzeni kweklinikhi.Kwiimeko ezinzima, kunokukhokelela ekungaphumeleli kokuphefumla kunye nokufa.Ugqirha ukhumbuze ukuba akufuneki usele utywala kwiiveki ezimbini emva kokutya amayeza okubulala iintsholongwane, ungachukumisi amanzi e-Huoxiang Zhengqi kunye netshokolethi yeJiuxin, kwaye ulumkele ukusebenzisa iwayini ephuzi yerayisi xa upheka.
Ityhefu yeAcetaldehyde ebangelwa butywala
I-Disulfiram i-catalyst kwishishini lerabha.Kwangoko kwiminyaka engama-63 eyadlulayo, abaphandi baseCopenhagen bafumanisa ukuba xa abantu bechanabeke kwesi siselo sesiselo, banokuba nothotho lweempawu ezinjengokuqina kwesifuba, iintlungu zesifuba, ukubethabethana kwentliziyo kunye nokuphefumla nzima, ukugungxulwa kobuso, intloko ebuhlungu kunye nesiyezi, iintlungu zesisu. kunye nesicaphucaphu, ngoko bayibiza ngokuba "disulfiram njengempendulo".Kamva, i-disulfiram yaphuhliswa yaba lichiza lokuzikhwebula etywaleni, nto leyo eyenza abantu abanxila bangabuthandi utywala kwaye bahlukane nokuba likhoboka lotywala.
Ezinye izithako zonyango zikwanazo iikhemikhali ezinokwakheka kweekhemikhali ezifana ne-disulfiram.Emva kokuba i-ethanol ingena emzimbeni womntu, inkqubo yesiqhelo ye-metabolic ku-oxidize kwi-acetaldehyde esibindini, emva koko i-oxidize ibe yi-acetic acid.I-acetic acid kulula ukuba iqhubeke i-metabolized kwaye ikhutshwe ngaphandle komzimba.Nangona kunjalo, ukusabela kwe-disulfiram kwenza i-acetaldehyde ingakwazi ukuphinda ifakwe kwi-acetic acid, ekhokelela ekuqokeleleni kwe-acetaldehyde kubasebenzisi beziyobisi, ngaloo ndlela ibangela ityhefu.
Ixesha lokuposa: Aug-20-2021