Umthombo: 39 Health Network
Ithiphu eyinhloko: lapho ama-antibiotic e-cephalosporin neminye imithi ye-hypoglycemic ehlangana notshwala, angaholela ekuphenduleni kobuthi "njenge-disulfiram".Izinga lokungaxilongwa kahle kwalolu hlobo lokusabela ngobuthi liphezulu kakhulu lifinyelela ku-75%, futhi labo ababucayi bangafa.Udokotela ukhumbuza ukuthi akufanele uphuze utshwala emasontweni amabili ngemva kokuthatha ama-antibiotics, futhi ungathinti ukudla okudakayo nezidakamizwa ezifana namanzi e-Huoxiang Zhengqi noshokoledi we-Jiuxin.
Umkhuhlane kanye namakhaza kwakubanjelwa ekhaya izinsuku ezimbalwa.Ngemva kokwelashwa, abantu abangaba ngu-35 ababethulula isifuba babephuza ndawonye;Ngemva kokudla izidakamizwa ze-hypoglycemic, phuza iwayini elincane ukuze uqede izinkanuko... Lokhu akuvamile emadodeni amaningi.Nokho, ochwepheshe baxwayise ngokuyekethiswa “iwayini elincane” ngemva kokugula.
Enyangeni edlule, amadoda amaningi e-Guangzhou abe nezimpawu zokuphuza njengokushaya kwenhliziyo, ukucinana kwesifuba, ukujuluka, isiyezi, ubuhlungu besisu kanye nokuhlanza etafuleni lewayini.Kodwa-ke, lapho beya esibhedlela, bathola ukuthi abanabo utshwala, izifo zenhliziyo ne-cerebrovascular nezinye izinkinga.Kwavela ukuthi ngaphambi kokuba baye esidlweni sakusihlwa, babephuze ama-antibiotics kanye nezidakamizwa ze-hypoglycemic.
Odokotela baveze ukuthi ngemva kokuthatha ama-antibiotic e-cephalosporin, i-imidazole derivatives, i-sulfonylureas kanye ne-biguanides, lapho ivezwe otshwaleni, kuzoholela kule “disulfiram efana nokusabela” okuye kwanganakwa isikhathi eside emtholampilo.Ezimweni ezimbi kakhulu, kungaholela ekuhlulekeni kokuphefumula ngisho nokufa.Udokotela ukhumbuze ukuthi akufanele uphuze utshwala emasontweni amabili ngemva kokudla ama-antibiotics, ungawathinti amanzi e-Huoxiang Zhengqi noshokoledi we-Jiuxin, futhi qaphela ukusebenzisa iwayini eliphuzi elayisi lapho upheka.
Ubuthi be-acetaldehyde obubangelwa utshwala
I-Disulfiram iyisisusa embonini yenjoloba.Eminyakeni engu-63 edlule, abacwaningi baseCopenhagen bathola ukuthi uma abantu abachayeka kulesi siphuzo bephuza, bangaba nochungechunge lwezimpawu ezinjengokucinana kwesifuba, ubuhlungu besifuba, ukushaya kwenhliziyo nokuphelelwa umoya, ukuqunjelwa ubuso, ikhanda nesiyezi, ubuhlungu besisu. kanye nesicanucanu, ngakho bayiqamba ngokuthi “i-disulfiram njengokusabela”.Kamuva, i-disulfiram yathuthukiswa yaba isidakamizwa sokuzithiba ophuzweni, okwenza izidakwa zingabuthandi utshwala futhi zihlukane nokuba umlutha wotshwala.
Ezinye izithako zemithi nazo zinamakhemikhali anesakhiwo samakhemikhali esifana ne-disulfiram.Ngemuva kokuthi i-ethanol ingene emzimbeni womuntu, inqubo evamile ye-metabolic iwukuba i-oxidize ibe i-acetaldehyde esibindini, bese i-oxidize ibe i-acetic acid.I-acetic acid kulula ukuqhubekela phambili i-metabolized futhi ikhishwe ngaphandle komzimba.Kodwa-ke, ukusabela kwe-disulfiram kwenza i-acetaldehyde ingakwazi ukuqhubeka i-oxidized ibe i-acetic acid, okuholela ekuqongeleleni kwe-acetaldehyde kubasebenzisi bezidakamizwa, ngaleyo ndlela ibangele ubuthi.
Isikhathi sokuthumela: Aug-20-2021