Cov neeg mob uas tsis yog mob hnyav nrog tus mob coronavirus tshiab: heparin anticoagulation vs pa tiv thaiv thrombus

Tau qhov twg los: Ntiaj teb no tshuaj compilation sij hawm: Cuaj hlis 18, 2021

Feem ntau cov neeg mob ntsws tshiab mob ntsws muaj mob me me thiab pib tsis xav tau kev txhawb nqa hauv nruab nrog cev hauv ICU.Novel coronavirus pneumonia tau siv los ntawm kev tshawb fawb ntawm N Engl J Med thaum Lub Yim Hli 2021. Cov kws tshawb fawb hauv Canada, Tebchaws Meskas thiab Brazil tau luam tawm cov ntaub ntawv Suav thaum ub tshawb fawb txog kev kho cov tshuaj tiv thaiv kab mob ntawm heparin anticoagulation therapy hauv cov neeg mob uas tsis mob hnyav nrog mob ntsws tshiab.

Keeb kwm: Tus kab mob coronavirus tshiab yog txuam nrog kev tuag thiab muaj teeb meem vim thrombosis thiab o.Cov kws tshawb fawb tau pom tias tus kab mob coronavirus tshiab tuaj yeem txhim kho cov txiaj ntsig ntawm cov neeg mob tsis tseem ceeb hauv tsev kho mob nrog cov mob ntsws tshiab.

Cov hau kev: cov kab mob coronavirus tshiab (tsis yog kev txhawb nqa hauv nruab nrog cev), txhais tau tias yog qib kev saib xyuas tsis tseem ceeb, tau muab tso rau 2 lub ntsiab lus siv: heparin anticoagulation lossis thrombus prophylaxis tsis tu ncua hauv qhov qhib, hloov kho, ntau lub platform, tswj kev sim.Cov txiaj ntsig tseem ceeb yog cov hnub uas tsis muaj kev txhawb nqa lub cev, ntsuas los ntawm qhov ntsuas sib txuas ua ke uas ua ke hauv tsev kho mob tuag (tus qhab nia - 1) thiab cov hnub ntawm cov neeg mob uas muaj sia nyob kom tso tawm yam tsis muaj lub plawv lossis lub ntsws ua pa txhawb nqa mus txog hnub 21. Tag nrho cov txiaj ntsig ntawm tus neeg mob tau raug soj ntsuam los ntawm kev siv Bayesian statistical qauv thiab raws li cov theem pib D-dimer.

Cov txiaj ntsig: thaum cov koob tshuaj ntawm cov tshuaj anticoagulation tau ntsib cov txheej txheem preset superiority, qhov kev sim tau nres.Ntawm 2219 tus neeg mob hauv qhov kev ntsuam xyuas zaum kawg, qhov tshwm sim ntawm kev kho mob koob tshuaj anticoagulation nce cov hnub tsis muaj kev txhawb nqa hauv nruab nrog cev piv nrog cov pa thromboprophylaxis yog 98.6% (kho lossis, 1.27; 95% CI, 1.03 ~ 1.58).Qhov sib txawv kiag li ntawm cov pab pawg hauv kev hloov kho kom muaj sia nyob kom tso tawm yam tsis muaj kev txhawb nqa hauv nruab nrog cev tau pom tias cov tshuaj kho cov tshuaj anticoagulation zoo dua, thiab qhov sib txawv ntawm ob pawg yog 4.0% (0.5 ~ 7.2).Qhov kawg tshwm sim ntawm qhov zoo tshaj ntawm kev kho tshuaj anticoagulation tshaj cov pa thromboprophylaxis yog 97.3%, 92.9% thiab 97.3% hauv siab D-dimer cohort, qis D-dimer cohort thiab tsis paub D-dimer cohort, feem.Loj hemorrhage tshwm sim nyob rau hauv 1.9% thiab 0.9% ntawm cov neeg mob nyob rau hauv kev kho mob koob tshuaj anticoagulation pab pawg neeg thiab thrombosis tiv thaiv pab pawg neeg, feem.

Xaus: cov tswv yim tshiab coronavirus mob ntsws tuaj yeem ua rau muaj qhov tshwm sim ntawm kev muaj sia nyob thiab tso tawm thiab txo qis kev siv cov hlab plawv lossis kev ua pa rau cov neeg mob uas tsis muaj mob ntsws tshiab.


Post lub sij hawm: Sep-18-2021