Puna: ka manawa hui ʻana o ka lāʻau lapaʻau honua: Kepakemapa 18, 2021
ʻO ka hapa nui o nā mea maʻi maʻi maʻi maʻi coronavirus maʻi maʻi maʻi a ʻaʻole pono i ke kākoʻo kino i ka ICU.Ua hoʻohana ʻia ʻo Novel coronavirus pneumonia ma ke aʻo ʻana o N Engl J Med i ʻAukake 2021. Ua hoʻopuka nā mea noiʻi ma Kanada, ʻAmelika Hui Pū ʻIa a me Brazil i ka ʻimi ʻana i nā palapala Kina kahiko no ka hopena anticoagulant lapaʻau o ka heparin anticoagulation therapy i nā poʻe maʻi maʻi ʻole me ka maʻi maʻi lei aliʻi hou.
Ka hope: pili ka maʻi pneumonia novel coronavirus me ka make a me nā pilikia ma muli o ka thrombosis a me ka mumū.Ua manaʻo ka poʻe noiʻi e hiki ke hoʻomaikaʻi i ka hopena o nā maʻi maʻi maʻi maʻi koʻikoʻi ʻole me ka maʻi pneumonia lei hou.
Nā ʻano hana: novel coronavirus pneumonia (non organ support), i wehewehe ʻia he pae mālama koʻikoʻi ʻole, ua hāʻawi wale ʻia i 2 wehewehe pono: heparin anticoagulation a i ʻole thrombus prophylaxis maʻamau i kēia hamama, adaptive, multi platform, controlled trial.ʻO ka hopena mua ʻo ka helu o nā lā me ke kākoʻo ʻole o ke kino, i loiloi ʻia e ka helu sequential i hui pū ʻia i ka make i loko o ka haukapila (helu - 1) a me ka helu o nā lā o nā maʻi i ola i ka hoʻokuʻu ʻana me ke kākoʻo ʻole o ka ʻōpū a i ʻole ka hanu a hiki i ka lā 21. Ua loiloi ʻia nā hopena maʻi āpau me ka hoʻohana ʻana i nā hiʻohiʻona helu Bayesian a ma muli o nā pae D-dimer baseline.
Nā hualoaʻa: i ka wā i hoʻokō ʻia ai ka nui o ka anticoagulation i nā koina preset superiority, ua kāpae ʻia ka hoʻāʻo.Ma waena o nā maʻi 2219 i ka loiloi hope loa, ʻo ka nui o ka lāʻau anticoagulation e hoʻonui ai i ka helu o nā lā me ke kākoʻo ʻole o ke kino i hoʻohālikelike ʻia me ka thromboprophylaxis maʻamau ʻo 98.6% (hoʻoponopono ʻia a i ʻole, 1.27; 95% CI, 1.03 ~ 1.58).ʻO ka ʻokoʻa loa ma waena o nā pūʻulu i ka hoʻoponopono ʻana i ke ola e hoʻokuʻu ʻia me ke kākoʻo ʻole o ke kino i hōʻike ʻia ʻoi aku ka maikaʻi o ka lāʻau lapaʻau o ka anticoagulation, a ʻo ka ʻokoʻa ma waena o nā hui ʻelua he 4.0% (0.5 ~ 7.2).ʻO ka hopena hope loa o ke kūlana kiʻekiʻe o ka lāʻau anticoagulation ma mua o ka thromboprophylaxis maʻamau he 97.3%, 92.9% a me 97.3% i ka hui D-dimer kiʻekiʻe, D-dimer cohort haʻahaʻa a me D-dimer cohort i ʻike ʻole ʻia.Ua loaʻa ka nui o ka hemorrhage ma 1.9% a me 0.9% o ka poʻe maʻi i ka hui anticoagulation a me ka hui pale thrombosis, kēlā me kēia.
Ka hopena: hiki i ka hoʻolālā maʻi maʻi coronavirus hou ke hoʻonui i ka hiki ke ola a hoʻokuʻu ʻia a hōʻemi i ka hoʻohana ʻana i ke kākoʻo cardiovascular a i ʻole ka hanu i nā mea maʻi me ka maʻi maʻi maʻi lei aliʻi hou ʻole.
Ka manawa hoʻouna: Sep-18-2021